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Evaluating the Role of Macrocycles in the Susceptibility of Hepatitis C Virus NS3/4A Protease Inhibitors to Drug Resistance

The hepatitis C virus (HCV) infects an estimated 150 million people worldwide and is the major cause of viral hepatitis, cirrhosis and liver cancer. The available antiviral therapies, which include pegylated-interferon, ribavirin and one of the HCV NS3/4A protease inhibitors telaprevir or boceprevir...

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Main Authors: Ali, Akbar, Aydin, Cihan, Gildemeister, Reinhold, Romano, Keith P., Cao, Hong, Özen, Ayşegül, Soumana, Djade, Newton, Alicia, Petropoulos, Christos J., Huang, Wei, Schiffer, Celia A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884027/
https://ncbi.nlm.nih.gov/pubmed/23594083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400100g
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