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Resistance Outside the Substrate Envelope: Hepatitis C NS3/4A Protease Inhibitors
Direct acting antivirals have dramatically increased the efficacy and tolerability of hepatitis C treatment, but drug resistance has emerged with some of these inhibitors, including non-structural protein 3/4A protease inhibitors (PIs). Although many co-crystal structures of PIs with the NS3/4A prot...
Guardat en:
| Publicat a: | Crit Rev Biochem Mol Biol |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7717897/ https://ncbi.nlm.nih.gov/pubmed/30821513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2019.1568962 |
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