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Molecular and Dynamic Mechanism Underlying Drug Resistance in Genotype 3 Hepatitis C NS3/4A Protease

Hepatitis C virus (HCV), affecting an estimated 150 million people worldwide, is the leading cause of viral hepatitis, cirrhosis and hepatocellular carcinoma. HCV is genetically diverse with six genotypes (GTs) and multiple subtypes of different global distribution and prevalence. Recent development...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Soumana, Djadé I., Yilmaz, Nese Kurt, Ali, Akbar, Prachanronarong, Kristina L., Schiffer, Celia A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221612/
https://ncbi.nlm.nih.gov/pubmed/27512818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b06454
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