The Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease Inhibitors

Hepatitis C virus (HCV) infects over 170 million people worldwide and is the leading cause of chronic liver diseases, including cirrhosis, liver failure, and liver cancer. Available antiviral therapies cause severe side effects and are effective only for a subset of patients, though treatment outcom...

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Autores principales: Romano, Keith P., Ali, Akbar, Aydin, Cihan, Soumana, Djade, Özen, Ayşegül, Deveau, Laura M., Silver, Casey, Cao, Hong, Newton, Alicia, Petropoulos, Christos J., Huang, Wei, Schiffer, Celia A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406087/
https://ncbi.nlm.nih.gov/pubmed/22910833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002832
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