Sources and Structures of Mitotic Crossovers That Arise When BLM Helicase Is Absent in Drosophila

The Bloom syndrome helicase, BLM, has numerous functions that prevent mitotic crossovers. We used unique features of Drosophila melanogaster to investigate origins and properties of mitotic crossovers that occur when BLM is absent. Induction of lesions that block replication forks increased crossove...

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Hlavní autoři: LaFave, Matthew C., Andersen, Sabrina L., Stoffregen, Eric P., Korda Holsclaw, Julie, Kohl, Kathryn P., Overton, Lewis J., Sekelsky, Jeff
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2014
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Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872178/
https://ncbi.nlm.nih.gov/pubmed/24172129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.158618
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