Sources and Structures of Mitotic Crossovers That Arise When BLM Helicase Is Absent in Drosophila

The Bloom syndrome helicase, BLM, has numerous functions that prevent mitotic crossovers. We used unique features of Drosophila melanogaster to investigate origins and properties of mitotic crossovers that occur when BLM is absent. Induction of lesions that block replication forks increased crossove...

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Detalhes bibliográficos
Main Authors: LaFave, Matthew C., Andersen, Sabrina L., Stoffregen, Eric P., Korda Holsclaw, Julie, Kohl, Kathryn P., Overton, Lewis J., Sekelsky, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872178/
https://ncbi.nlm.nih.gov/pubmed/24172129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.158618
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