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Drosophila FANCM Helicase Prevents Spontaneous Mitotic Crossovers Generated by the MUS81 and SLX1 Nucleases

Several helicases function during repair of double-strand breaks and handling of blocked or stalled replication forks to promote pathways that prevent formation of crossovers. Among these are the Bloom syndrome helicase BLM and the Fanconi anemia group M (FANCM) helicase. To better understand functi...

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Pubblicato in:Genetics
Autori principali: Kuo, H. Kenny, McMahan, Susan, Rota, Christopher M., Kohl, Kathryn P., Sekelsky, Jeff
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224181/
https://ncbi.nlm.nih.gov/pubmed/25205745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.168096
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