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Drosophila FANCM Helicase Prevents Spontaneous Mitotic Crossovers Generated by the MUS81 and SLX1 Nucleases

Several helicases function during repair of double-strand breaks and handling of blocked or stalled replication forks to promote pathways that prevent formation of crossovers. Among these are the Bloom syndrome helicase BLM and the Fanconi anemia group M (FANCM) helicase. To better understand functi...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Kuo, H. Kenny, McMahan, Susan, Rota, Christopher M., Kohl, Kathryn P., Sekelsky, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224181/
https://ncbi.nlm.nih.gov/pubmed/25205745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.168096
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