Sources and Structures of Mitotic Crossovers That Arise When BLM Helicase Is Absent in Drosophila

The Bloom syndrome helicase, BLM, has numerous functions that prevent mitotic crossovers. We used unique features of Drosophila melanogaster to investigate origins and properties of mitotic crossovers that occur when BLM is absent. Induction of lesions that block replication forks increased crossove...

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Bibliografske podrobnosti
Main Authors: LaFave, Matthew C., Andersen, Sabrina L., Stoffregen, Eric P., Korda Holsclaw, Julie, Kohl, Kathryn P., Overton, Lewis J., Sekelsky, Jeff
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2014
Teme:
Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872178/
https://ncbi.nlm.nih.gov/pubmed/24172129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.158618
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