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Three Structure-Selective Endonucleases Are Essential in the Absence of BLM Helicase in Drosophila

DNA repair mechanisms in mitotically proliferating cells avoid generating crossovers, which can contribute to genome instability. Most models for the production of crossovers involve an intermediate with one or more four-stranded Holliday junctions (HJs), which are resolved into duplex molecules thr...

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Detalhes bibliográficos
Main Authors: Andersen, Sabrina L., Kuo, H. Kenny, Savukoski, Daniel, Brodsky, Michael H., Sekelsky, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192830/
https://ncbi.nlm.nih.gov/pubmed/22022278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002315
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