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Three Structure-Selective Endonucleases Are Essential in the Absence of BLM Helicase in Drosophila

DNA repair mechanisms in mitotically proliferating cells avoid generating crossovers, which can contribute to genome instability. Most models for the production of crossovers involve an intermediate with one or more four-stranded Holliday junctions (HJs), which are resolved into duplex molecules thr...

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Bibliographic Details
Main Authors: Andersen, Sabrina L., Kuo, H. Kenny, Savukoski, Daniel, Brodsky, Michael H., Sekelsky, Jeff
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192830/
https://ncbi.nlm.nih.gov/pubmed/22022278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002315
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