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Synthetic Lethality of Drosophila in the Absence of the MUS81 Endonuclease and the DmBlm Helicase Is Associated With Elevated Apoptosis
Mus81-Mms4 (Mus81-Eme1 in some species) is a heterodimeric DNA structure-specific endonuclease that has been implicated in meiotic recombination and processing of damaged replication forks in fungi. We generated and characterized mutations in Drosophila melanogaster mus81 and mms4. Unlike the case i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Copyright © 2007 by the Genetics Society of America
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950608/ https://ncbi.nlm.nih.gov/pubmed/17603121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.070060 |
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