The DNA repair endonuclease Mus81 facilitates fast DNA replication in the absence of exogenous damage

The Mus81 endonuclease resolves recombination intermediates and mediates cellular responses to exogenous replicative stress. Here, we show that Mus81 also regulates the rate of DNA replication during normal growth by promoting replication fork progression while reducing the frequency of replication...

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Publicado no:Nat Commun
Main Authors: Fu, Haiqing, Martin, Melvenia M., Regairaz, Marie, Huang, Liang, You, Yang, Lin, Chi-Mei, Ryan, Michael, Kim, RyangGuk, Shimura, Tsutomu, Pommier, Yves, Aladjem, Mirit I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400873/
https://ncbi.nlm.nih.gov/pubmed/25879486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7746
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