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Telomere recombination requires the MUS81 endonuclease
Telomerase-negative cancer cells maintain their telomeres via the Alternative Lengthening of Telomeres (ALT) pathway1–3. Although a growing body of evidence demonstrates that the ALT mechanism is a post-replicative telomere recombination process, molecular details of this pathway are largely unknown...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2675667/ https://ncbi.nlm.nih.gov/pubmed/19363487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1867 |
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