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Mus81/Mms4 endonuclease and Sgs1 helicase collaborate to ensure proper recombination intermediate metabolism during meiosis

Budding yeast lacking the Sgs1 helicase and the Mus81/Mms4 endonuclease are inviable, and indirect studies implicate homologous recombination gone awry as the cause of death. We show that mutants lacking both enzymes have profound defects in meiotic recombination intermediate metabolism and crossove...

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Hlavní autoři: Jessop, Lea, Lichten, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584117/
https://ncbi.nlm.nih.gov/pubmed/18691964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.05.021
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