BLM helicase ortholog Sgs1 is a central regulator of meiotic recombination intermediate metabolism

The BLM helicase has been shown to maintain genome stability by preventing accumulation of aberrant recombination intermediates. We show here that the Saccharomyces cerevisiae BLM ortholog, Sgs1, plays an integral role in normal meiotic recombination, beyond its documented activity limiting aberrant...

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Hauptverfasser: De Muyt, Arnaud, Jessop, Lea, Kolar, Elizabeth, Sourirajan, Anuradha, Chen, Jianhong, Dayani, Yaron, Lichten, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328772/
https://ncbi.nlm.nih.gov/pubmed/22500736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.02.020
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