Temporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage

The structure-specific Mus81-Eme1/Mms4 endonuclease contributes importantly to DNA repair and genome integrity maintenance. Here, using budding yeast, we have studied its function and regulation during the cellular response to DNA damage and show that this endonuclease is necessary for successful ch...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Saugar, Irene, Vázquez, María Victoria, Gallo-Fernández, María, Ortiz-Bazán, María Ángeles, Segurado, Mónica, Calzada, Arturo, Tercero, José Antonio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2013
Pynciau:
Genome Integrity, Repair and Replication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799426/
https://ncbi.nlm.nih.gov/pubmed/23901010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt645
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