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Temporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage

The structure-specific Mus81-Eme1/Mms4 endonuclease contributes importantly to DNA repair and genome integrity maintenance. Here, using budding yeast, we have studied its function and regulation during the cellular response to DNA damage and show that this endonuclease is necessary for successful ch...

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Bibliografiske detaljer
Main Authors: Saugar, Irene, Vázquez, María Victoria, Gallo-Fernández, María, Ortiz-Bazán, María Ángeles, Segurado, Mónica, Calzada, Arturo, Tercero, José Antonio
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799426/
https://ncbi.nlm.nih.gov/pubmed/23901010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt645
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