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Cell cycle-dependent regulation of the nuclease activity of Mus81–Eme1/Mms4
The conserved heterodimeric endonuclease Mus81–Eme1/Mms4 plays an important role in the maintenance of genomic integrity in eukaryotic cells. Here, we show that budding yeast Mus81–Mms4 is strictly regulated during the mitotic cell cycle by Cdc28 (CDK)- and Cdc5 (Polo-like kinase)-dependent phosphor...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458551/ https://ncbi.nlm.nih.gov/pubmed/22730299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks599 |
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