Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein

MUS81-EME1 is a DNA endonuclease involved in replication-coupled repair of DNA interstrand cross-links (ICLs). A prevalent hypothetical role of MUS81-EME1 in ICL repair is to unhook the damage by incising the leading strand at the 3′ side of an ICL lesion. In this study, we report that purified MUS8...

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Detalhes bibliográficos
Main Authors: Benitez, Anaid, Yuan, Fenghua, Nakajima, Satoshi, Wei, Leizhen, Qian, Liangyue, Myers, Richard, Hu, Jennifer J., Lan, Li, Zhang, Yanbin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919598/
https://ncbi.nlm.nih.gov/pubmed/24170812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt975
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