Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress

The MUS81 complex is crucial for preserving genome stability through the resolution of branched DNA intermediates in mitosis. However, untimely activation of the MUS81 complex in S-phase is dangerous. Little is known about the regulation of the human MUS81 complex and how deregulated activation affe...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Palma, Anita, Pugliese, Giusj Monia, Murfuni, Ivana, Marabitti, Veronica, Malacaria, Eva, Rinalducci, Sara, Minoprio, Anna, Sanchez, Massimo, Mazzei, Filomena, Zolla, Lello, Franchitto, Annapaola, Pichierri, Pietro
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007509/
https://ncbi.nlm.nih.gov/pubmed/29850896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky280
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