Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress

The MUS81 complex is crucial for preserving genome stability through the resolution of branched DNA intermediates in mitosis. However, untimely activation of the MUS81 complex in S-phase is dangerous. Little is known about the regulation of the human MUS81 complex and how deregulated activation affe...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Palma, Anita, Pugliese, Giusj Monia, Murfuni, Ivana, Marabitti, Veronica, Malacaria, Eva, Rinalducci, Sara, Minoprio, Anna, Sanchez, Massimo, Mazzei, Filomena, Zolla, Lello, Franchitto, Annapaola, Pichierri, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007509/
https://ncbi.nlm.nih.gov/pubmed/29850896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky280
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