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Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
Stabilisation of stalled replication forks prevents excessive fork reversal and their pathological degradation, which can undermine genome integrity. Here we investigate a physiological role of RAD52 at stalled replication forks by using human cell models depleted of RAD52, a specific small-molecule...
Tallennettuna:
| Julkaisussa: | Nat Commun |
|---|---|
| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group UK
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6441034/ https://ncbi.nlm.nih.gov/pubmed/30926821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09196-9 |
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