Survival of the Replication Checkpoint Deficient Cells Requires MUS81-RAD52 Function

In checkpoint-deficient cells, DNA double-strand breaks (DSBs) are produced during replication by the structure-specific endonuclease MUS81. The mechanism underlying MUS81-dependent cleavage, and the effect on chromosome integrity and viability of checkpoint deficient cells is only partly understood...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Murfuni, Ivana, Basile, Giorgia, Subramanyam, Shyamal, Malacaria, Eva, Bignami, Margherita, Spies, Maria, Franchitto, Annapaola, Pichierri, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814295/
https://ncbi.nlm.nih.gov/pubmed/24204313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003910
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados