Cargando...
Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway
Failure to stabilize and properly process stalled replication forks results in chromosome instability, which is a hallmark of cancer cells and several human genetic conditions that are characterized by cancer predisposition. Loss of WRN, a RecQ-like enzyme mutated in the cancer-prone disease Werner...
Guardado en:
| Autores principales: | , , , , , |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Rockefeller University Press
2008
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2568021/ https://ncbi.nlm.nih.gov/pubmed/18852298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200803173 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|