Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair

Individuals with Fanconi anemia (FA) are susceptible to bone marrow failure, congenital abnormalities, cancer predisposition and exhibit defective DNA crosslink repair. The relationship of this repair defect to disease traits remains unclear, given that crosslink sensitivity is recapitulated in FA m...

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Autors principals: Larin, Meghan, Gallo, David, Tamblyn, Laura, Yang, Jay, Liao, Hudson, Sabat, Nestor, Brown, Grant W., McPherson, J. Peter
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Genome Integrity, Repair and Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150781/
https://ncbi.nlm.nih.gov/pubmed/25056314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku676
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