Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair

Individuals with Fanconi anemia (FA) are susceptible to bone marrow failure, congenital abnormalities, cancer predisposition and exhibit defective DNA crosslink repair. The relationship of this repair defect to disease traits remains unclear, given that crosslink sensitivity is recapitulated in FA m...

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Detalhes bibliográficos
Main Authors: Larin, Meghan, Gallo, David, Tamblyn, Laura, Yang, Jay, Liao, Hudson, Sabat, Nestor, Brown, Grant W., McPherson, J. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150781/
https://ncbi.nlm.nih.gov/pubmed/25056314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku676
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