Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair

Individuals with Fanconi anemia (FA) are susceptible to bone marrow failure, congenital abnormalities, cancer predisposition and exhibit defective DNA crosslink repair. The relationship of this repair defect to disease traits remains unclear, given that crosslink sensitivity is recapitulated in FA m...

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Main Authors: Larin, Meghan, Gallo, David, Tamblyn, Laura, Yang, Jay, Liao, Hudson, Sabat, Nestor, Brown, Grant W., McPherson, J. Peter
格式: Artigo
語言:Inglês
出版: Oxford University Press 2014
主題:
Genome Integrity, Repair and Replication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150781/
https://ncbi.nlm.nih.gov/pubmed/25056314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku676
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