Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair

Individuals with Fanconi anemia (FA) are susceptible to bone marrow failure, congenital abnormalities, cancer predisposition and exhibit defective DNA crosslink repair. The relationship of this repair defect to disease traits remains unclear, given that crosslink sensitivity is recapitulated in FA m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Larin, Meghan, Gallo, David, Tamblyn, Laura, Yang, Jay, Liao, Hudson, Sabat, Nestor, Brown, Grant W., McPherson, J. Peter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2014
Pynciau:
Genome Integrity, Repair and Replication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150781/
https://ncbi.nlm.nih.gov/pubmed/25056314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku676
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