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The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair
Fanconi anemia (FA) is a genetic disease characterized by bone marrow failure and increased cancer risk. The FA proteins function primarily in DNA interstrand crosslink (ICL) repair. Here, we have examined the role of the PTEN phosphatase in this process. We have established that PTEN-deficient cell...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5098254/ https://ncbi.nlm.nih.gov/pubmed/27819275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36439 |
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