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Modulation of the Fanconi anemia pathway via chemically induced changes in chromatin structure
Fanconi anemia (FA) is a rare disease characterized by congenital defects, bone marrow failure, and atypically early-onset cancers. The FA proteins function cooperatively to repair DNA interstrand crosslinks. A major step in the activation of the pathway is the monoubiquitination of the FANCD2 and F...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5652718/ https://ncbi.nlm.nih.gov/pubmed/29100324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19470 |
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