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Regulation of the Fanconi anemia pathway by a CUE ubiquitin-binding domain in the FANCD2 protein
The Fanconi anemia (FA)–BRCA pathway is critical for the repair of DNA interstrand crosslinks (ICLs) and the maintenance of chromosome stability. A key step in FA-BRCA pathway activation is the covalent attachment of monoubiquitin to FANCD2 and FANCI. Monoubiquitinated FANCD2 and FANCI localize in c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437598/ https://ncbi.nlm.nih.gov/pubmed/22855611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-410472 |
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