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Fanconi anemia and the repair of Watson and Crick crosslinks

Fanconi anemia (FA) proteins function in maintaining genomic stability. Their major role is in the repair of DNA interstrand crosslinks, which by virtue of covalently binding the Watson and Crick strands of DNA, impede replication and transcription. Inappropriately repaired interstrand crosslinks ca...

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Detalhes bibliográficos
Main Authors: Kottemann, Molly C., Smogorzewska, Agata
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700363/
https://ncbi.nlm.nih.gov/pubmed/23325218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11863
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