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Fanconi anemia and the repair of Watson and Crick crosslinks
Fanconi anemia (FA) proteins function in maintaining genomic stability. Their major role is in the repair of DNA interstrand crosslinks, which by virtue of covalently binding the Watson and Crick strands of DNA, impede replication and transcription. Inappropriately repaired interstrand crosslinks ca...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3700363/ https://ncbi.nlm.nih.gov/pubmed/23325218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11863 |
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