Identification of the Fanconi anemia (FANC) I protein, a monoubiquitinated FANCD2 paralog required for crosslink repair

Fanconi anemia (FA) is a developmental and cancer-predisposition syndrome caused by mutations in genes controlling crosslink repair. Several FA proteins form a ubiquitin ligase that controls monoubiquitination of the FANCD2 protein in an ATR-dependent manner. Here we describe a new FA protein FANCI,...

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Main Authors: Smogorzewska, Agata, Matsuoka, Shuhei, Vinciguerra, Patrizia, McDonald, E. Robert, Hurov, Kristen E., Luo, Ji, Ballif, Bryan A., Gygi, Steven P., Hofmann, Kay, D’Andrea, Alan D., Elledge, Stephen J.
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175179/
https://ncbi.nlm.nih.gov/pubmed/17412408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.03.009
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