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The Fanconi anemia pathway in replication stress and DNA crosslink repair

Interstand crosslinks (ICLs) are DNA lesions where the bases of opposing DNA strands are covalently linked, inhibiting critical cellular processes such as transcription and replication. Chemical agents that generate ICLs cause chromosomal abnormalities including breaks, deletions and rearrangements,...

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Detalles Bibliográficos
Main Authors: Jones, Mathew J. K., Huang, Tony T.
Formato: Artigo
Idioma:Inglês
Publicado: SP Birkhäuser Verlag Basel 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890373/
https://ncbi.nlm.nih.gov/pubmed/22744751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1051-0
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