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The Fanconi anemia pathway in replication stress and DNA crosslink repair
Interstand crosslinks (ICLs) are DNA lesions where the bases of opposing DNA strands are covalently linked, inhibiting critical cellular processes such as transcription and replication. Chemical agents that generate ICLs cause chromosomal abnormalities including breaks, deletions and rearrangements,...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
SP Birkhäuser Verlag Basel
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3890373/ https://ncbi.nlm.nih.gov/pubmed/22744751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1051-0 |
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