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Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4
SLX4, the newly identified Fanconi anemia protein, FANCP, is implicated in repairing DNA damage induced by DNA interstrand cross-linking (ICL) agents, topoisomerase I (TOP1) inhibitors, and in Holliday junction resolution. It interacts with and enhances the activity of XPF-ERCC1, MUS81-EME1, and SLX...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3538331/ https://ncbi.nlm.nih.gov/pubmed/23093618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-441212 |
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