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Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4

SLX4, the newly identified Fanconi anemia protein, FANCP, is implicated in repairing DNA damage induced by DNA interstrand cross-linking (ICL) agents, topoisomerase I (TOP1) inhibitors, and in Holliday junction resolution. It interacts with and enhances the activity of XPF-ERCC1, MUS81-EME1, and SLX...

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Detalhes bibliográficos
Main Authors: Kim, Yonghwan, Spitz, Gabriella S., Veturi, Uma, Lach, Francis P., Auerbach, Arleen D., Smogorzewska, Agata
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538331/
https://ncbi.nlm.nih.gov/pubmed/23093618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-441212
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