Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4

SLX4, the newly identified Fanconi anemia protein, FANCP, is implicated in repairing DNA damage induced by DNA interstrand cross-linking (ICL) agents, topoisomerase I (TOP1) inhibitors, and in Holliday junction resolution. It interacts with and enhances the activity of XPF-ERCC1, MUS81-EME1, and SLX...

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Bibliografiske detaljer
Main Authors: Kim, Yonghwan, Spitz, Gabriella S., Veturi, Uma, Lach, Francis P., Auerbach, Arleen D., Smogorzewska, Agata
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2013
Fag:
Hematopoiesis and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538331/
https://ncbi.nlm.nih.gov/pubmed/23093618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-441212
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