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The nuclease FAN1 is involved in DNA crosslink repair in Arabidopsis thaliana independently of the nuclease MUS81

Fanconi anemia is a severe genetic disorder. Mutations in one of several genes lead to defects in DNA crosslink (CL) repair in human cells. An essential step in CL repair is the activation of the pathway by the monoubiquitination of the heterodimer FANCD2/FANCI, which recruits the nuclease FAN1 to t...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Herrmann, Natalie J., Knoll, Alexander, Puchta, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402529/
https://ncbi.nlm.nih.gov/pubmed/25779053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv208
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