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Mus81 Endonuclease Localizes to Nucleoli and to Regions of DNA Damage in Human S-phase Cells
Mus81 is a highly conserved substrate specific endonuclease. Human Mus81 cleaves Holliday junctions, replication forks, and 3′ flap substrates in vitro, suggesting a number of possible in vivo functions. We show here that the abundance of human Mus81 peaks in S-phase and remains high in cells that h...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC284787/ https://ncbi.nlm.nih.gov/pubmed/14638871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-05-0276 |
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