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Mus81 Endonuclease Localizes to Nucleoli and to Regions of DNA Damage in Human S-phase Cells

Mus81 is a highly conserved substrate specific endonuclease. Human Mus81 cleaves Holliday junctions, replication forks, and 3′ flap substrates in vitro, suggesting a number of possible in vivo functions. We show here that the abundance of human Mus81 peaks in S-phase and remains high in cells that h...

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Detalles Bibliográficos
Main Authors: Gao, Hui, Chen, Xiao-Bo, McGowan, Clare H.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC284787/
https://ncbi.nlm.nih.gov/pubmed/14638871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-05-0276
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