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Formation of deletions during double-strand break repair in Drosophila DmBlm mutants occurs after strand invasion
Bloom syndrome is a rare disorder associated with cancer predisposition and genomic instability and is caused by loss of the RecQ helicase BLM. The Drosophila ortholog of BLM (DmBlm) is required for accurate repair of DNA double-strand gaps by homologous recombination. Repair products from DmBlm mut...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2004
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524851/ https://ncbi.nlm.nih.gov/pubmed/15501916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406157101 |
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