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Formation of deletions during double-strand break repair in Drosophila DmBlm mutants occurs after strand invasion
Bloom syndrome is a rare disorder associated with cancer predisposition and genomic instability and is caused by loss of the RecQ helicase BLM. The Drosophila ortholog of BLM (DmBlm) is required for accurate repair of DNA double-strand gaps by homologous recombination. Repair products from DmBlm mut...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524851/ https://ncbi.nlm.nih.gov/pubmed/15501916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406157101 |
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