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Evolution of a MCM complex in flies promoting meiotic crossovers by blocking BLM helicase

Generation of meiotic crossovers in many eukaryotes requires the elimination of anti-crossover activities by utilizing the Msh4–Msh5 heterodimer to block helicases. Msh4 and Msh5 have been lost from the flies Drosophila and Glossina but we identified a complex of mini-chromosome maintenance (MCM) pr...

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Detalhes bibliográficos
Main Authors: Kohl, Kathryn P., Jones, Corbin D., Sekelsky, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599781/
https://ncbi.nlm.nih.gov/pubmed/23224558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1228190
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