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Safety, pharmacokinetics and pharmacodynamics of multiple oral doses of apixaban, a factor Xa inhibitor, in healthy subjects

AIM: Apixaban is an oral factor Xa inhibitor approved for stroke prevention in atrial fibrillation and thromboprophylaxis in patients who have undergone elective hip or knee replacement surgery and under development for treatment of venous thromboembolism. This study examined the safety, pharmacokin...

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Autors principals: Frost, Charles, Nepal, Sunil, Wang, Jessie, Schuster, Alan, Byon, Wonkyung, Boyd, Rebecca A, Yu, Zhigang, Shenker, Andrew, Barrett, Yu Chen, Mosqueda-Garcia, Rogelio, LaCreta, Frank
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853536/
https://ncbi.nlm.nih.gov/pubmed/23451769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12106
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