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Effect of famotidine on the pharmacokinetics of apixaban, an oral direct factor Xa inhibitor

BACKGROUND: Apixaban is an oral, selective, direct factor Xa inhibitor approved for thromboprophylaxis after orthopedic surgery and stroke prevention in patients with atrial fibrillation, and under development for treatment of venous thromboembolism. This study investigated the effect of a gastric a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Upreti, Vijay V, Song, Yan, Wang, Jessie, Byon, Wonkyung, Boyd, Rebecca A, Pursley, Janice M, LaCreta, Frank, Frost, Charles E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637032/
https://ncbi.nlm.nih.gov/pubmed/23637566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S41999
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