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Safety, pharmacokinetics and pharmacodynamics of multiple oral doses of apixaban, a factor Xa inhibitor, in healthy subjects

AIM: Apixaban is an oral factor Xa inhibitor approved for stroke prevention in atrial fibrillation and thromboprophylaxis in patients who have undergone elective hip or knee replacement surgery and under development for treatment of venous thromboembolism. This study examined the safety, pharmacokin...

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Main Authors: Frost, Charles, Nepal, Sunil, Wang, Jessie, Schuster, Alan, Byon, Wonkyung, Boyd, Rebecca A, Yu, Zhigang, Shenker, Andrew, Barrett, Yu Chen, Mosqueda-Garcia, Rogelio, LaCreta, Frank
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853536/
https://ncbi.nlm.nih.gov/pubmed/23451769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12106
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