Investigation of age-related changes in LMNA splicing and expression of progerin in human skeletal muscles

Age-related changes in splice-forms of LMNA, which encodes the nuclear lamina proteins lamin A/C, have not been investigated in skeletal muscle. In the rare premature ageing disease, Hutchinson-Gilford progeria syndrome (HGPS), de novo point mutations in LMNA activate a cryptic splice site in exon 1...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Luo, Yue-Bei, Mitrpant, Chalermchai, Johnsen, Russell D, Fabian, Victoria A, Fletcher, Sue, Mastaglia, Frank L, Wilton, Steve D
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2013
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843258/
https://ncbi.nlm.nih.gov/pubmed/24294364
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars