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Upregulation of the aging related LMNA splice variant progerin in dilated cardiomyopathy
BACKGROUND: Mutations in the LMNA gene are a common cause (6–8%) of dilated cardiomyopathy (DCM) leading to heart failure, a growing health care problem worldwide. The premature aging disease Hutchinson-Gilford syndrome (HGPS) is also caused by defined mutations in the LMNA gene resulting in activat...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5922532/ https://ncbi.nlm.nih.gov/pubmed/29702688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196739 |
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