Upregulation of the aging related LMNA splice variant progerin in dilated cardiomyopathy

BACKGROUND: Mutations in the LMNA gene are a common cause (6–8%) of dilated cardiomyopathy (DCM) leading to heart failure, a growing health care problem worldwide. The premature aging disease Hutchinson-Gilford syndrome (HGPS) is also caused by defined mutations in the LMNA gene resulting in activat...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Messner, Moritz, Ghadge, Santhosh Kumar, Goetsch, Valentina, Wimmer, Andreas, Dörler, Jakob, Pölzl, Gerhard, Zaruba, Marc-Michael
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922532/
https://ncbi.nlm.nih.gov/pubmed/29702688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196739
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares