Upregulation of the aging related LMNA splice variant progerin in dilated cardiomyopathy

BACKGROUND: Mutations in the LMNA gene are a common cause (6–8%) of dilated cardiomyopathy (DCM) leading to heart failure, a growing health care problem worldwide. The premature aging disease Hutchinson-Gilford syndrome (HGPS) is also caused by defined mutations in the LMNA gene resulting in activat...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Messner, Moritz, Ghadge, Santhosh Kumar, Goetsch, Valentina, Wimmer, Andreas, Dörler, Jakob, Pölzl, Gerhard, Zaruba, Marc-Michael
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922532/
https://ncbi.nlm.nih.gov/pubmed/29702688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196739
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы