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ZMPSTE24 Is Associated with Elevated Inflammation and Progerin mRNA
Lamins are important filaments forming the inner nuclear membrane. Lamin A is processed by zinc metalloproteinase (ZMPSTE24). Failure to cleave a truncated form of prelamin A—also called progerin—causes Hutchinson–Gilford progeria syndrome a well-known premature aging disease. Minor levels of proger...
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| Publicado no: | Cells |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7563344/ https://ncbi.nlm.nih.gov/pubmed/32872320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9091981 |
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