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Smooth Muscle Specific Ablation of CXCL12 in Mice Downregulates CXCR7 Associated with Defective Coronary Arteries and Cardiac Hypertrophy

The chemokine CXCL12 plays a fundamental role in cardiovascular development, cell trafficking, and myocardial repair. Human genome-wide association studies even have identified novel loci downstream of the CXCL12 gene locus associated with coronary artery disease and myocardial infarction. Neverthel...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ghadge, Santhosh Kumar, Messner, Moritz, Seiringer, Herbert, Maurer, Thomas, Staggl, Simon, Zeller, Tanja, Müller, Christian, Börnigen, Daniela, Weninger, Wolfgang J., Geyer, Stefan H., Sopper, Sieghart, Krogsdam, Anne, Pölzl, Gerhard, Bauer, Axel, Zaruba, Marc-Michael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8198701/
https://ncbi.nlm.nih.gov/pubmed/34072818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115908
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