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Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24

The nuclear lamins form a karyoskeleton providing structural rigidity to the nucleus. One member of the lamin family, lamin A, is first synthesized as a 74 kDa precursor, prelamin A. After the endopeptidase and methylation reactions which occur after farnesylation of the CAAX-box cysteine, there is...

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Main Authors: Corrigan, Douglas P., Kuszczak, Danuta, Rusinol, Antonio E., Thewke, Douglas P., Hrycyna, Christine A., Michaelis, Susan, Sinensky, Michael S.
格式: Artigo
語言:Inglês
出版: Portland Press Ltd. 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134940/
https://ncbi.nlm.nih.gov/pubmed/15479156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041359
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