Investigation of splicing changes and post-translational processing of LMNA in sporadic inclusion body myositis

Some features of sporadic inclusion body myositis (s-IBM) suggest that there is acceleration of the normal ageing process in muscle tissue. LMNA encodes the nuclear lamina proteins lamin A/C through alternative splicing, and aberrant splicing of exon 11 leads to the premature ageing disease, Hutchin...

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Bibliografische gegevens
Hoofdauteurs: Luo, Yue-Bei, Mitrpant, Chalermchai, Johnsen, Russell, Fabian, Vicki, Needham, Merrilee, Fletcher, Sue, Wilton, Steve D, Mastaglia, Frank L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2013
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759479/
https://ncbi.nlm.nih.gov/pubmed/24040437
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