טוען...
LRRK2 secretion in exosomes is regulated by 14-3-3
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene cause late-onset Parkinson's disease (PD). Emerging evidence suggests a role for LRRK2 in the endocytic pathway. Here, we show that LRRK2 is released in extracellular microvesicles (i.e. exosomes) from cells that natively express LRRK2....
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3836478/ https://ncbi.nlm.nih.gov/pubmed/23886663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt346 |
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