Differential LRRK2 Expression in the Cortex, Striatum, and Substantia Nigra in Transgenic and Nontransgenic Rodents

Mutations in leucine-rich repeat kinase 2 (LRRK2) are found in a significant proportion of late-onset Parkinson’s disease (PD) patients. Elucidating the neuroanatomical localization of LRRK2 will further define LRRK2 function and the molecular basis of PD. Here, we utilize recently characterized mon...

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Autori principali: West, Andrew B., Cowell, Rita M., Daher, João P.L., Moehle, Mark S., Hinkle, Kelly M., Melrose, Heather L., Standaert, David G., Volpicelli-Daley, Laura A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076169/
https://ncbi.nlm.nih.gov/pubmed/24633735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23583
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