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Abrogation of α-synuclein–mediated dopaminergic neurodegeneration in LRRK2-deficient rats
Missense mutations in the leucine-rich repeat kinase 2 (LRRK2) gene can cause late-onset Parkinson disease. Past studies have provided conflicting evidence for the protective effects of LRRK2 knockdown in models of Parkinson disease as well as other disorders. These discrepancies may be caused by un...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4078806/ https://ncbi.nlm.nih.gov/pubmed/24927544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403215111 |
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